INTRACELLULAR OSTEOPONTIN PROTECTS FROM AUTOIMMUNITY-DRIVEN LYMPHOMA DEVELOPMENT INHIBITING TLR9-MYD88-STAT3 SIGNALING

Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling

Abstract Background Autoimmune disorders, including Systemic Lupus Erythematosus (SLE), are associated with increased incidence of hematological malignancies.The matricellular protein osteopontin (OPN) has been linked to SLE pathogenesis, as SLE patients show increased serum levels of OPN and often polymorphisms in its gene.Although widely studied

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The Imperative of Social Security in Time of Insecurity in Nigeria

The Nigerian ryan garcia funko state has been having insecurity challenges at different times since independence but the recent wave of insecurity has taken different and outrageous dimension.Today, loss of lives and properties in the hands of insurgents are no longer news because we have lost count with the numbers of deaths.With the combined effo

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Urban-rural differences in immunisation status and associated demographic factors among children 12-59 months in a southwestern state, Nigeria.

Vaccine preventable diseases (VPDs) are a leading course of child under-five mortality in sub-Saharan Africa.A target of 95% immunization coverage is necessary for the sustained control of VPDs.This study aims to determine the immunization status and its associated demo-graphic factors among children 12-59 months old in Akinyele Local Government ar

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